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Enterobacteriaceae "family"
The Enterobacteriaceae
family contain more than one hundred genus of bacteria, the most important are "proteus
species; E coli; Klebsiella species; Enterobacter
species ,Salmonella species, Shigella species….etc;"Antibiotic use for treatment of the infection caused
by Enterobacteriaceae "in general"
1- Ampicillin
2- Cefazolin or Cephalothin
3- Gentamicin or Tobramycin
4- Amikacin
5- Amoxicillin – Clavulanic acid
6- Piperacillin – tazobactam
7- Ticarcillin – Clavulanic acid
8- Cefuroxime
9- Cefepime
10- Cefotetan
or Cefoxitin
11- Cefotaxime
or Ceftriaxone
12- Ciprofloxacin
13-Levofloxacin
14- Ertapenem or Imipenem or Meropenem
15- Piperacillin
16- Trimethoprime – Sulphamethoxazole
17- Aztreonam
18- Ceftazidime
19- Chloramphenicol
20-tetracycline
For urinary tract infection
1- Lomefloxacin
2- Norfloxacin
3- Nitrofurantion
4-Sulfisoxazole
5- Trimethoprime
Enterobacteriaceae
species are usually susceptible to Carbapenems In general Enterobacteriaceae
that are resistant to any second generation Cephalosporin's are resistant to
first generation of Cephalosporin'sAlso Enterobacteriaceae
which are resistant to any third generation cephalosporin are resistant to
first and second generation Cephalosporin's [other than Cephamycin]The Enterobacteriaceae
bacteria species are resistant to third generation of cephalosporin by
producing an enzyme called "Extended – spectrum β-lactamase";
also there is another mechanism of resistance The "extended
– spectrum B lactamase" [ESBL] are clavulanate – inhibited transferable enzymes
able to hydrolyse third and fourth generation cephalosporin (ex cefotaxime, Ceftazidime,
Ceftriaxone)Many ESBL
producers strains are multi-resistant to quinolones, amino glycosides , and
other B-Lactamase inhibitor combination
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موضوع: Enterobacteriaceae "family" 
