بسم الله الرحمن الرحيم
Analysis of pancreatic hormones
Analysis of the hormone insulin (Insulin)
Introduction:
The
hormone insulin, the hormone protein produced by beta cells (β) in the
islets of Langerhans pancreas, which is responsible for the consumption
and reduce the level of glucose (sugar) in the blood, and therefore is
determined by its level and the level of pre-insulin (Proinsulin) and
its components (C-peptide) in disease diabetes
(Diabetes Mellitus) / are given at the hormone insulin deficiency by
injecting blood and not through the mouth because it is easy to break
down protein in the stomach.
Dependent
process of secretion of the hormone insulin is entirely dependent on
the level of glucose in the blood, if the level of glucose in the blood
high, the secretion of this hormone increases, which means that there
Tnsaba directly proportional, and adopt the process of excretion and
response cells of the pancreas on the ions (+ + Ca) and entry to the
pancreas.
The functions of insulin:
Roles of insulin such as:
Metabolism of sugars.
Influence on many metabolic processes and on the target cells (the cells that affect the hormone insulin) and target cells are:
- Cells of the liver.
- Muscle cells.
- The fat cells.
Normal ranges for hormone insulin is between (5-25 IU / L)
Ranges from the level before insulin between (0.05 - 0.5 ng / ml).
Level ranges (C-peptide) between (1-4 nano-g / ml).
Measure does not use insulin for the diagnosis of diabetes.
Required measurement of the hormone insulin in the following cases:
For the diagnosis of Alinsulinoma (Insulinoma).
See if there was a stock and a functional of the pancreas, especially in diabetes in young people.
Reasons for the high level of the hormone insulin:
In the case of Alinsulinoma.
Cushing's disease.
Intolerance to fructose and galactose.
Sometimes in the obese.