بسم الله الرحمن الرحيم
Streptococcus pneumonia
The antibiotics used for treatment of infections with Streptococcus pneumonia
1- Erythromycin 2- Penicillin
3- Trimethoprime – Sulphamethoxazole
4- Cefepime MIC
5- Cefotaxime MIC
6- Ceftriaxone MIC
7- Clindamycin
8- Gemifloxacin
9- Levofloxacin
10- Ofloxacin
11- Moxifloxacin
12- Meropenem MIC
13- Telithromycin
14- Tetracycline
15- Vancomycin
16- Amoxicillin MIC
17- Amoxicillin – Clavulanic acid MIC
18- Chloramphenicol
19- Ertapenem MIC
20- Imipenem MIC
21- Cefuroxime MIC
22- Linezolid
Streptococcus pneumonia is intrinsically resistant to Trimethoprime (only)
Only result of Penicillin, Vancomycin , (Cefotaxime or Ceftriaxone) and Meropenem should be reported from Streptococcus pneumonia from cerebrospinal fluid.
Streptococcus pneumonia with an interpretation of resistance for fluoroquinolone or third generation cephalosporin are uncommon or may result from technical errors.
Amoxicillin; Ampicillin; Cefepime; Cefotaxime ; Ceftriaxone ; Cefuroxime ; Ertapenem ; Imipenem ; and Meropenem ; may be used for treatment of pneumococcal infections; however reliable disk diffusion susceptibility test with those agents do not yet exist, there in vitro activity is best determined using MIC method.
Isolates of pneumococcal with Oxacillin (1mg) disk methods and zone of inhibition >20 mm are susceptible to penicillin and can be considered susceptible to Ampicillin, amoxicillin , amoxicillin – Clavulanic acid, Ampicillin – Sulbactam , cefaclor , Cefdinir , Cefuroxime , cefpodoxime , Cefepime , Cefotaxime , Ceftriaxone , Imipenem and Meropenem.